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劉興國 Liu Xingguo

中國科學(xué)院廣州生物醫(yī)藥與健康研究院

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劉興國,,男,博士,,研究員,,博士生導(dǎo)師,國家自然科學(xué)基金優(yōu)秀青年獲得者,,中科院""百人計劃""獲得者,,廣東省自然科學(xué)杰出青年基金獲得者,,廣東省特支計劃中青年科技領(lǐng)軍人才,,2016年干細(xì)胞青年研究員獎和國際生物物理學(xué)會""2011 Young Bioenergeticist Award""獲得者(每年只有一人獲此獎項),,國際學(xué)術(shù)雜志Frontiers in Genetics of Aging、Int J Stem Cell Res Transp,、Biophysics編委,,Plos One、FEBS Letters,、Cell Regeneration,、Bioresource Technol、Biotechnol Bioeng審稿人,。2007年1月獲得清華大學(xué)博士學(xué)位,,2007-2010年在美國Thomas Jefferson University做博士后研究,2010年至今在中國科學(xué)院廣州生物醫(yī)藥與健康研究院擔(dān)任研究員,、博導(dǎo),。以第一或通訊作者身份在Cell Metabolism、Hepatology,、EMBO J、Cell Death & Diff,、Mol Cell等國際雜志上發(fā)表22篇論文,,申請專利9項(其中1項PCT)。承擔(dān)973項目,、國家自然科學(xué)基金,、中國科學(xué)院戰(zhàn)略性先導(dǎo)科技專項等10項國家和地方的基金支持,9次在國際學(xué)術(shù)會議上做大會特邀報告,任第9屆亞洲線粒體研究與醫(yī)學(xué)國際研討會組委會成員,。

 

代表性論文:

1. Zhongfu Ying, Keshi Chen, Lingjun Zheng, Yi Wu, Linpeng Li, Rui Wang, Qi Long, Liang Yang,  Jingyi Guo, Deyang Yao, Yong Li, Feixiang Bao, Ge Xiang, Jinglei Liu, Qiaoying Huang, Zhiming Wu, Andrew Paul Hutchins, Duanqing Pei and Xingguo Liu*. Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming. Cell Metabolism. 2016, 23(1): 220-226.

2. Shengbiao Li, Jingyi Guo, Zhongfu Ying , Shen Chen, Liang Yang, Keshi Chen, Qi Long, Dajiang Qin, Duanqing Pei, Xingguo Liu*. Valproic Acid-Induced Hepatotoxicity in Alpers Syndrome Is Associated With Mitochondrial Permeability Transition Pore Opening-Dependent Apoptotic Sensitivity in an Induced Pluripotent Stem Cell Model. Hepatology. 2015, 61(5): 1730-1739.

3. Ge Xiang, Liang Yang, Qi Long, Keshi Chen, Haite Tang, Yi Wu, Zihuang Liu, Yanshuang Zhou, Juntao Qi, Lingjun Zheng, Wenbo Liu, Zhongfu Ying, Weimin Fan, Hongyan Shi, Hongmei Li, Xiaobing Lin, Mi Gao, Jinglei Liu, Feixiang Bao, Linpeng Li, Lifan Duan, Min Li & Xingguo Liu*. BNIP3L-dependent Mitophagy Accounts for Mitochondrial Clearance during SKO-induced Somatic Cell Reprogramming. Autophagy. 2017, 13(9): 1543-1555.

4. Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Sch?ler, Guoliang Xu, Xingguo Liu*, Duanqing Pei*. FRAP screening identifies Gadd45a as a heterochromatin relaxer that enhances iPSC generation. EMBO Reports. 2016, 17(11): 1641-1656. 

5. Xingguo Liu, David Weaver, Orian Shirihai and Gy?rgy Hajnóczky. Mitochondrial ""kiss-and-run"": interplay between mitochondrial motility and fusion fission dynamics. EMBO J. 2009, 28 (20): 3074-3089."

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